Compare experts › Stacy Sims vs Bryan Johnson

Stacy Sims vs Bryan Johnson

Stacy Sims (exercise physiologist) and Bryan Johnson (entrepreneur, founder of blueprint) side by side: how they train, eat, supplement and sleep, how strong the evidence is, and how to build a plan from either or both.

Words explained (13)
Zone 2
Steady cardio at a pace where you can still talk in full sentences, but not sing.
Intervals
Short hard efforts with easy recovery in between, such as 30 seconds fast, 90 seconds slow.
4 × 4
Four rounds of 4 minutes hard with 3 minutes easy in between. Also called Norwegian intervals.
Loaded carry
Walking while holding something heavy, like shopping bags or dumbbells.
Mobility
Moving your joints freely through their full range.
Creatine
A well-studied supplement that supports strength and muscle.
Omega-3 (EPA, DHA)
Healthy fats found mostly in oily fish such as salmon, herring and sardines.
Fibre
The part of plant foods you don't digest. It feeds healthy gut bacteria and keeps you full.
Time-restricted eating
Eating all your meals within a set window of the day, for example 8am to 6pm.
Glucose
Blood sugar.
Perimenopause
The years of changing hormones before periods stop for good.
Hormone therapy (HRT, MHT)
Medicine that replaces hormones that fall at menopause. Only a doctor can prescribe it.
Rapamycin, metformin
Prescription drugs that some experts take hoping to slow ageing. Not proven for that, and never part of your plan.

At a glance

MeasureStacy SimsBryan Johnson
BackgroundExercise physiologistEntrepreneur, founder of Blueprint
Training split60% strength · 10% aerobic · 25% intervals · 5% mobility30% strength · 40% aerobic · 20% intervals · 10% mobility
Signature habitHeavy lifts + sprintsSleep-first, measure everything
Protein~2.2 g/kg~130 g a day
Training styleWomen 40+Measure everything
Overall evidenceStrongMixed
FollowingInstagram 1.4M · YouTube 372KInstagram 2.8M · YouTube 2.2M

Training splits are our estimates from each expert’s published routine. Following checked October 2026.

The key differences

  • Sims puts more of the week into strength: about 60% against 30%.
  • Johnson puts more of the week into aerobic base (zone 2): about 40% against 10%.
  • In plans in their style, Sims' hard sessions are short sprints; Johnson's are 4-minute intervals (Norwegian 4 × 4).
  • We rate the evidence behind Sims' protocol higher: strong, against mixed for Johnson.
  • Supplements that go into a plan: Sims, creatine monohydrate; Johnson, creatine monohydrate, omega-3. Prescription items and personal stacks stay out of every plan.
  • Only Johnson has a mobility or movement routine of their own.

Protocols side by side

Each line is rated for the evidence behind it. “Doctor only” items never go into a plan.

Training

Stacy Sims

  • Strength training 3–4 times a week, 45–60 minutes, built on compound liftsStrong evidence
  • From perimenopause, lift heavy: about 3–5 sets of 6 reps or fewer, leaving 2–3 reps in reserve, with 2+ minutes restSome evidence
  • Sprint intervals of 30 seconds or less, all-out, with full recovery; 1–2 sessions a weekSome evidence
  • Jump and impact work (e.g. squat jumps, box jumps) for bone; one studied protocol is 10–20 jumps twice a daySome evidence
  • Keep easy cardio (walking, easy rides) as recovery; she plays down long moderate-intensity sessions and zone 2 for midlife body-composition goalsPersonal habit
  • 'Ten-minute rule': if you still feel flat after a 10-minute warm-up, scale the session downPersonal habit

Bryan Johnson

  • About 150 minutes a week of moderate cardio (Zone 2, a pace where you can still talk)Strong evidence
  • About 75 minutes a week of vigorous work such as high-intensity intervalsStrong evidence
  • Strength training 3 times a weekStrong evidence
  • Balance, flexibility and mobility work included in the daily sessionSome evidence
  • 2–3 minutes of light movement every 30 minutes of sitting, plus two 10-minute walks a daySome evidence
  • He says even 20 minutes of exercise a day is worthwhile for people starting outNote

Eating

Stacy Sims

  • Do not train fasted: about 15 g protein before lifting, plus about 30 g carbohydrate before cardio of up to an hourSome evidence
  • After training: 40–60 g protein (perimenopause on) within about 45 minutes, and carbohydrate within 2 hoursSome evidence
  • Daily protein around 2.2 g/kg body weight, the top of the 1.4–2.2 g/kg range in her ISSN position standSome evidence
  • Protein at meals 30–40 g, snacks 15–20 gSome evidence
  • Avoid long fasts, keto and big calorie cuts if active; a small deficit (about 150–200 kcal) in the evening, away from training, if aiming to lose fatPersonal habit

Bryan Johnson

  • About 2,250 kcal a day, which he describes as roughly 10% below his energy needsSome evidence
  • About 130 g protein a day, much of it from plant foods, protein powders and collagenPersonal habit
  • Lots of vegetables, legumes (black lentils, chickpeas), berries, nuts and extra-virgin olive oil (about 1 tbsp per meal)Strong evidence
  • All food eaten between about 5:30 am and noonPersonal habit
  • Stops drinking fluids at about 4 pm to avoid waking at nightPersonal habit
  • Follows no named diet; he says he avoids labels such as vegan or ketoNote

Supplements

Stacy Sims

  • Creatine monohydrate 3–5 g a day (start with 1–2 g if unsure), paired with strength trainingStrong evidence
  • Choose third-party tested products (NSF or Informed Sport)Note
  • Vitamin D3, omega-3, collagen and turmeric mentioned as options; no doses givenPersonal habit
  • Iron only if a blood test shows low ferritinDoctor only

Bryan Johnson

  • Creatine, 7.5 g a day in totalSome evidence
  • Omega-3 (EPA/DHA), 800 mg a daySome evidence
  • Fibre-type prebiotics (inulin, galacto-oligosaccharides, arabinogalactan) in his morning drinkPersonal habit
  • Ashwagandha and rhodiolaPersonal habit
  • Blueprint's own multi-ingredient capsules and antioxidant softgelsPersonal habit
  • Collagen powder; he suggests 20–30 g a day for skin and hairPersonal habit

Sleep & recovery

Stacy Sims

  • Traditional (Finnish-style) sauna at about 60–80 °C after training; she prefers heat to cold for womenSome evidence
  • If using cold water, choose cool (about 16 °C) rather than ice-coldPersonal habit
  • Treat easy days as true recovery between hard sessionsPersonal habit
  • Sees hormone therapy as a valid option for hot flushes and bone risk, but not required for every womanDoctor only

Bryan Johnson

  • Fixed early schedule: in bed about 8:30 pm, up about 4:30 amStrong evidence
  • Screens off and a 60-minute wind-down before bedSome evidence
  • No caffeine for 8–10 hours before sleepSome evidence
  • Bright light soon after waking and dim red or amber light in the eveningSome evidence
  • Dry sauna at about 79 °C for 20 minutes dailySome evidence
  • Tracks sleep with a wearable and aims for a very low resting heart rate before sleepPersonal habit

Stress & mind

Stacy Sims

  • Keep hard intervals short; she says longer efforts and very long sessions raise cortisol, already a concern in menopauseSome evidence
  • In perimenopause, have caffeine with food before training if it makes you shaky or light-headedPersonal habit
  • Listen to your own body and track responses rather than following a fixed planPersonal habit

Bryan Johnson

  • Uses a fixed routine so daily health choices do not depend on willpowerPersonal habit
  • Breathwork or reading as part of the evening wind-downSome evidence

Brain health

Stacy Sims

  • Creatine for brain fog and mood; she cites a trial where 5 g a day added to an antidepressant helped women with depressionSome evidence
  • Favours truly hard intervals over moderate or zone 2 cardio for midlife cognitive and metabolic benefitsSome evidence

Bryan Johnson

No specific guidance in what we reviewed.

Weak spots to know

Stacy Sims

  • Some researchers say her sex-specific advice goes beyond the evidence. A 2023 umbrella review co-authored by Stuart Phillips found no clear effect of menstrual-cycle phase on strength or training gains, and Sims publicly debated Lauren Colenso-Semple in 2025 on fasted training and protein timing, framed as mechanisms versus outcomes.
  • Her case against fasted training leans heavily on short-term hormone and appetite responses; critics note that longer studies measuring actual fat loss and muscle gain show little difference when daily calories are adequate.
  • Many of her menopause-specific prescriptions (exact sprint lengths, playing down zone 2, tight post-exercise protein windows) come from extrapolation and her own coaching experience rather than trials in midlife women.

Bryan Johnson

  • His results come from one person doing many things at once, so it is hard to tell which part works. Scientists including Nir Barzilai (Nature, republished by Scientific American, 2026), who said science can't rest on a single person, and Morgan Levine (quoted in Vice, reported by Lifespan.io, 2023) have made this point.
  • His 'speed of ageing' and biological-age figures come from epigenetic clocks and biomarker comparisons. Researchers such as Steve Horvath have noted that some of these clocks predict health outcomes less well than others, and none is yet proven as a measure of whether a treatment extends life.
  • Several therapies he has tried, such as young-donor plasma and rapamycin, he later dropped himself. The US FDA has warned that young-plasma infusions have no proven benefit and may cause harm.

Build a plan from Sims, Johnson or both

Your free plan shows a week of gym sessions, cardio, a day of eating, supplements and mobility, fitted to your age, time and health.

Questions

What is the main difference between Stacy Sims and Bryan Johnson?

Their training split differs most in strength: Sims about 60%, Johnson about 30% (our estimate from their published routines). Sims' signature habit is Heavy lifts + sprints; Johnson's is Sleep-first, measure everything.

How much protein do Sims and Johnson recommend?

Sims: ~2.2 g/kg. Johnson: ~130 g a day.

Whose advice has stronger evidence?

We rate the evidence behind Sims' protocol higher: strong, against mixed for Johnson.

Do Sims and Johnson disagree?

Not directly in what we reviewed. Their differences are in emphasis: sims puts more of the week into strength: about 60% against 30%.

Can I combine Sims and Johnson?

Yes. In Build my mix you choose one expert per area, for example one for strength and another for eating. Your free plan shows the result straight away.

More comparisons

Full sources are on each profile: Stacy Sims · Bryan Johnson. Reviewed October 2026.